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AESTHETIC RAYS · 06 / 13 · Biology

It Keeps Changing, Yet Holds Together

How does a little rod under the microscope keep living? A quiet shape need not mean that nothing is happening.

In this essay

Enlarge the microscope image and a small rod appears on the screen. It has no expression and makes no gesture toward the camera. At first there seems little to watch.

It is the fission yeast Schizosaccharomyces pombe. In time-lapse footage, the cell elongates at its ends. During division a septum forms across the middle. Eventually the cell separates into two.

Pause the recording midway and there is simply a rod. Let time back in, and the rod is no longer something placed there and left alone. It takes up material, metabolizes, grows and maintains the boundary of a living cell.

Its recognizable shape does not mean that nothing is happening inside it.

Quiet can be busy

We are familiar with another way of keeping things. Put an object somewhere safe, handle it sparingly, protect it from conditions that damage it. Ideally, it will look much the same when we take it out next year.

A cell cannot stay alive in that fashion. Stopping its exchanges does not finally secure it against change. Once the activities it needs have ceased, a shape may temporarily remain, but something essential has changed.

A tree offers a larger instance. Seen from a window, it seems simply to stand there. Meanwhile leaves, branches and roots grow and change at different rates; material is absorbed, transformed and transported. Its parts do not all follow one replacement schedule. Nor does a day arrive when all the material has neatly been exchanged. Continuity is maintained through activities running at different speeds.

This complicates the phrase “still the same one.”

Preservation need not mean sealing away the original material. Some things must keep changing in order to continue. The stillness we see can be the visible result of activities that have not come apart.

Calling this the resilience of life may miss something. Resilience suggests a contest, survival against adversity, a victory after hardship. No catastrophe is necessary here. A cell growing ordinarily under favorable conditions is already doing what we are considering.

A line appears across the middle

The footage continues. A septum forms, separation is completed, and there are two cells where there was one.

Nobody cuts the cell in half from outside and assembles two replacements. Growth, the allocation of cellular material and the establishment of boundaries take place through the cell's activities. The resulting cells are not fragments awaiting external repair. They can continue growing and enter subsequent cycles.

Yet neither is a whole second life of an unchanged original individual. What continues is a pattern of living activity, not one permanent name magically occupying two places.

Look inward: material comes and goes while the cell maintains itself. Look along the lineage: new cells take up activities of this kind. The same question appears in two locations. How does changing material participate in a continuity rather than simply dispersing what was there?

This is not a test that every living individual must pass by reproducing. That would turn an observable relation into a standard for deciding whose life qualifies. Here we are following one instance in which maintenance and continuation can be seen together.

Neither must we say the cell seeks eternity or willingly sacrifices itself for descendants. The footage supplies no such motives. Growth, separation and further growth already give us enough to attend to.

No little person inside

The word “itself” can easily acquire too much human meaning.

We start to imagine a smaller proprietor inside the cell, knowing what should happen next and pressing the appropriate controls. In trying to explain life, we install an invisible manager.

No such manager is needed. Metabolism, regulation, growth and division are the activities under investigation. Learning how they occur does not make life disappear.

The opposite shortcut is equally unhelpful. Inability to calculate exactly what a cell will do next does not establish freedom or subjecthood. Measurements may be inadequate; models may omit relevant conditions. Differences between apparently similar cells cannot, by themselves, settle which explanation is responsible.

The source paper offers a stronger philosophical reading: what a living thing maintains and passes on is not something external conditions can exhaustively account for without loss. It places this irreducible aspect at the center of biological beauty.

That is a claim the argument undertakes to defend, not another organ already photographed through the microscope. We can follow its invitation to look while leaving the claim open to challenge. Smuggling it inside the phrase “science has proved” would borrow an authority the essay has not earned.

Observing that a cell maintains itself and proving that an external explanation can never exhaust it therefore remain different achievements. The first gives the discussion a concrete place to begin. It does not automatically deliver the second.

Attractiveness is not the only entrance

Some living things readily invite affection: soft fur, a leaf unfolding toward us, a small animal that seems curious. Feeling arrives almost before attention has settled.

Fission yeast enjoys none of these advantages. Without its label, the footage may look monotonous. It need not compensate by proving that it is useful to humanity.

A biologist may study the cell cycle with it. A producer may ask what yield a microorganism can provide. Those activities have their own importance. This essay pauses somewhere slightly different: before asking what the organism accomplishes for us, it asks how it continues as this living thing.

Understanding the mechanisms helps. Many relevant processes are not visible in a few frames; experiments and extended research are needed to distinguish them. Beauty does not require pretending the camera has shown more than it has. Knowing what comes from the image and what comes from research can make attention more dependable.

Then there may be a moment in which no knowledge is added. We already knew that the cell divides and had learned the terminology. This time, however, we are not hurrying to answer an examination question or calculate a yield. We attend to a boundary taking shape.

The cell not yet separated and the two newly separated cells can both repay attention. Suspense does not make the former superior. Completion does not make the latter dull. An activity has accomplished this stage; the new cells can each continue. That established condition has something to show as well.

There may be no remarkable feeling. You can finish the recording, close the screen and do something else. Nobody needs to labor at feeling awe before a little rod.

But the next time you say it was doing nothing, merely being there, you might pause.

Something was happening all along. It remained not because the world had forgotten to disturb it, but through the activities of its life.